The “bad” cholesterol: lower is better

Bottom line:

Too much bad cholesterol in the blood can lead to fatty plaques which obstruct arteries and could lead to cardiovascular diseases. It is a huge market, for “bad” cholesterol-lowering drugs. Novel approaches could provide a solution for patients unable to take statins, who represent 15 to 20% of patients.
New mechanisms of action have been identified, and drugs in development have the potential to be more effective and safer. DNA and RNA Gene therapy offer the possibility to treat the root cause of the disease. As is often the case, drugs combination are usually the most successful, resulting in strong M&A / partnership activity.

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